Case Studies

The cases/ directory in the repository contains crystal structure prediction (CSP) results for 6 organic molecules studied in the Genarris 3.0 paper.

Molecules Studied

Molecule

CSD Refcode

Z

Space Group

Aspirin (Form I)

ACSALA

4

P2₁/c

Aspirin (Form II)

ACSALA19

4

Pna2₁

ε-CL-20

PUBMUU12

4

P2₁/n

2,4-DNI

DATGIP

4

Pbca

δ-HMX

OCHTET13

2

P2₁/n

Target I

1

P1̄

Target XXII

2

P2₁/c

Each case includes:

  • Experimental structures – From the Cambridge Structural Database (CSD)

  • Generated structures – CIF files of crystal structures generated by Genarris and relaxed using MACE-OFF23 and PBE+MBD

  • Analysis data – Total energies from MACE-OFF23 and PBE+MBD methods

Applications

Genarris has been applied to a wide range of molecular crystal studies:

📦 Project

📝 Description

🔗 Links

⚡ FastCSP

Accelerated Molecular Crystal Structure Prediction with UMA

📄 arXiv, 💻 Code

💎 OMC25

Open Molecular Crystals 2025 — 27M+ molecular crystal structures

📄 DOI, 📊 Dataset